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Application Guide 2026-08-28 2 min read

Magnesium Sulfate Heptahydrate (CAS 10034-99-8): Epsom Salt Chemistry, ACS Specifications, and Application Notes

Practical guide to magnesium sulfate heptahydrate: drying-agent use, ACS reagent specifications, agricultural and nutritional roles, and storage guidance.

Magnesium sulfate heptahydrate — Epsom salt — is one of the most frequently used inorganic salts in laboratory practice, where it serves as the default drying agent for organic extracts, a magnesium source in synthesis, and a standard component of buffer and culture systems. The same compound supports large-scale applications in agriculture, nutrition, and industrial processes.

Chemical Identity and Key Properties

PropertyValue
CAS Number10034-99-8
Molecular FormulaH14MgO11S
Molecular Weight246.01 g/mol
Density1.68 @25 °C
Typical Purity≥98%, 98.0-102.0% (ACS specification)

Laboratory and Synthesis Uses

Drying Organic Phases

The heptahydrate is the workhorse neutral drying agent for ethereal and ester extracts: fast, coarse, easy to filter, and forgiving of acidic substrates. Its capacity for water is modest (the monohydrate is the end state at ambient drying), so best practice is a preliminary bulky pre-dry before the polish step.

Magnesium Source in Chemistry

From Grignard initiation support and magnesiation chemistry to precipitation protocols and sulfate/buffer systems, the salt is a convenient, safe Mg2+ vehicle.

Biochemical Media

Defined culture media use MgSO4·7H2O as the standard magnesium supplement at defined ionic strength.

Industrial and Agricultural Applications

In agriculture, magnesium sulfate corrects Mg deficiency in high-value crops and fertigation systems. Industrial uses include pulp-and-paper processing, textile dyeing, cement set-modifiers, and bath-salt/personal-care formulations.

Specifications and Storage

ACS-grade material meets defined assays (98.0–102.0% MgSO4·7H2O) with controlled insolubles, chloride, and heavy-metal limits; technical grades cover agricultural pricing tiers. The hydrate is stable in sealed containers but will cake or partially dehydrate under dry-heat or low-humidity extremes — store cool and sealed.

Frequently Asked Questions

Why is magnesium sulfate preferred over sodium sulfate for drying?

It acts faster than anhydrous sodium sulfate and suits acidic or fine-solid-sensitive workups; sodium sulfate holds more water per gram but dries more slowly.

What does ACS specification actually verify?

Assay within 98.0–102.0%, plus limits on insoluble matter, pH behavior, and trace metals — the appropriate choice for analytical and synthesis-critical workflows.

Can CoreyChem supply both reagent and agricultural grades?

Yes — multiple grades from ACS reagent to technical/agricultural scale are available with COA per lot.

Source from CoreyChem

CoreyChem supplies Magnesium Sulfate Heptahydrate (CAS 10034-99-8) with lot-specific COA and MSDS documentation. Custom synthesis, higher purity grades, and bulk packaging are available on request — contact our technical team with your target specification and quantity for current lead time and pricing.

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