(+)-8-Phenylmenthol (CAS 57707-91-2)
(+)-8-Phenylmenthol (CAS:
57707-91-2) has molecular formula C16H24O and molecular weight 232.36 g/mol. This compound has been the subject of numerous scientific investigations due to its structural features and practical utility in synthetic chemistry and industrial processes. View product details →
Product Background
This comprehensive research profile examines the scientific literature surrounding (+)-8-Phenylmenthol.
Key Research Findings
- Treatment of a suspension of polymer-supported chloroformate and piperidinone in the presence of Et3N resulted in attachment of the substrate onto the solid-support.
Detailed Literature Analysis
Below are the top-ranked research papers for (+)-8-Phenylmenthol, presented with bibliographic details and scientific abstracts.
Synthetic Chemistry
1. Polymer-supported (-)-8-phenylmenthyl Auxiliary as an Effective Solidphase Chiral Inductor in the Addition of Nucleophiles to N-acyliminium Ions.
AIM AND OBJECTIVE: According to our interest in developing new methods for the construction of intricate molecules, a reliable polymer-supported (-)-8-phenylmenthyl chiral auxiliary for the addition of different nucleophiles to chiral-supported N-acyliminium precursors were developed. MATERIALS AND METHODS: Merrifield resin was employed to anch
2. Diastereoselective anodic hetero- and homo-coupling of menthol-, 8-methylmenthol- and 8-phenylmenthol-2-alkylmalonates.
Diastereoselective radical coupling was achieved with chiral auxiliaries. The radicals were generated by anodic decarboxylation of five malonic acid derivatives. These were prepared from benzyl malonates and four menthol auxiliaries. Coelectrolyses with 3,3-dimethylbutanoic acid in methanol at platinum electrodes in an undivided cell afforded h
3. Synthesis of the Privileged 8-Arylmenthol Class by Radical Arylation of Isopulegol.
Hydrogen atom transfer (HAT) circumvents a disfavored Friedel-Crafts reaction in the derivatization of the inexpensive monoterpene isopulegol. A variety of readily prepared aryl and heteroaryl sulfonates undergo a formal hydroarylation to form 8-arylmenthols, privileged scaffolds for asymmetric synthesis, as typified by 8-phenylmenthol. High st
Other Research
4. Stereocontrolled Access to Quaternary Centers by Birch Reduction/Alkylation of Chiral Esters of Salicylic Acids.
8-Phenylmenthol esters of salicylic acid derivatives undergo efficient Birch reduction and in situ diastereoselective alkylations to afford methoxycyclohexadienes bearing new quaternary stereogenic centers. The use of an ester-based auxiliary is a designed improvement over the use of prolinol-derived amides, which are expensive and often very d
Conclusion
The research literature on (+)-8-Phenylmenthol demonstrates sustained scientific interest, with publications continuing through 0. The compound serves as an important building block in synthetic chemistry and has been explored for various applications. Researchers and industrial users can view detailed specifications or submit an inquiry for pricing and availability.
Data Sources: PubMed/MEDLINE, CrossRef. 4 papers analyzed. Last updated: 2026-05-25. This article is automatically generated from peer-reviewed research data.