(+-)-Pantolactone (CAS 79-50-5)
(+-)-Pantolactone (CAS:
79-50-5) has molecular formula C6H10O3 and molecular weight 130.14 g/mol. This compound has been the subject of numerous scientific investigations due to its structural features and practical utility in synthetic chemistry and industrial processes. View product details →
Product Background
This comprehensive research profile examines the scientific literature surrounding (+-)-Pantolactone.
Key Research Findings
- Compared to the commercial immobilized D-lacs carrier, D-Lacs@ChNFM exhibited superior hydrolytic efficiency, higher batch stability, and excellent biodegradability.
- Our results are consistent with a role for canonical pantetheine at the outset of life on Earth.
Detailed Literature Analysis
Below are the top-ranked research papers for (+-)-Pantolactone, presented with bibliographic details and scientific abstracts.
Synthetic Chemistry
1. Sustainable chiral separation using chitin nanofibrous microspheres for enhanced catalysis and reusability.
The inefficiency and instability of free enzymes in the chiral separation of high-purity D-pantolactone, a crucial intermediate in vitamin B5 synthesis, pose significant challenges, with nanostructured materials offering promising solutions. In this study, D-Lactonohydrolase (D-lacs) was immobilized in crab-derived chitin nanofibrous microspheres (
2. Prebiotically plausible chemoselective pantetheine synthesis in water.
Coenzyme A (CoA) is essential to all life on Earth, and its functional subunit, pantetheine, is important in many origin-of-life scenarios, but how pantetheine emerged on the early Earth remains a mystery. Earlier attempts to selectively synthesize pantetheine failed, leading to suggestions that "simpler" thiols must have preceded pantetheine at th
3. Enhancing the Catalytic Efficiency of D-lactonohydrolase through the Synergy of Tunnel Engineering, Evolutionary Analysis, and Force-Field Calculations.
Computational design advances enzyme evolution and their use in biocatalysis in a faster and more efficient manner. In this study, a synergistic approach integrating tunnel engineering, evolutionary analysis, and force-field calculations has been employed to enhance the catalytic activity of D-lactonohydrolase (D-Lac), which is a pivotal enzyme inv
Biological & Pharmacological Studies
4. Immobilizing D-lactonohydrolase with 3D-printed hollow filaments to improve the enzyme stability and reusability.
D-pantothenate is one of the essential micronutrients required by the organism. Stereoselective D-lactonohydrolase (D-lac) can hydrolyze DL-pantolactone into D-pantoic acid, the precursor of D-pantothenate. In this study, the D-lac gene from Fusarium moniliforme was heterogeneously expressed in Escherichia coli. Subsequently, coaxial 3D printing wa
Other Research
5. Pitfalls in the Optimization of Conformer Populations to Maximize the Similarity between Predicted and Experimental Chiroptical Spectra.
The conformational populations of pantolactone, epichlorohydrin, and
Conclusion
The research literature on (+-)-Pantolactone demonstrates sustained scientific interest, with publications continuing through 0. The compound serves as an important building block in synthetic chemistry and has been explored for various applications. Researchers and industrial users can view detailed specifications or submit an inquiry for pricing and availability.
Data Sources: PubMed/MEDLINE, CrossRef. 5 papers analyzed. Last updated: 2026-05-25. This article is automatically generated from peer-reviewed research data.