((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione) (CAS 151581-23-6)

((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione) (CAS: 151581-23-6) has molecular formula C16H22N4O3 and molecular weight 318.37 g/mol. This compound has been the subject of numerous scientific investigations due to its structural features and practical utility in synthetic chemistry and industrial processes. View product details →

Product Background

This comprehensive research profile examines the scientific literature surrounding ((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione).

Key Research Findings

  • In summary, influenza A virus infection profoundly inhibits capsaicin- and SP-induced relaxation responses, most likely by inhibiting the production of PGE.
  • It is concluded that both contraction- and relaxation-inducing prostanoid receptors are present in the in vitro preparation of feline basilar and middle cerebral artery.

Detailed Literature Analysis

Below are the top-ranked research papers for ((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione), presented with bibliographic details and scientific abstracts.

Synthetic Chemistry

1. Cerebrovascular effects of prostanoids: in-vitro studies in feline middle cerebral and basilar artery.
Whalley ET, Schilling L, Wahl M; Prostaglandins
The effect of prostaglandin (PG) E2, F2 alpha, the thromboxane-A2 mimetic U46619 (9,11-dideoxy-9 alpha,11 alpha-methanoepoxy-prostaglandin F2 alpha) and the prostacyclin mimetic iloprost was investigated in cat middle cerebral and basilar arteries in vitro precontracted with 5-hydroxytryptamine (5-HT) (50nM) in the absence and presence of the c

Biological & Pharmacological Studies

2. Influence of influenza A infection on capsaicin-induced responses in murine airways.
Taylor SJ, Mann TS, Henry PJ; J Pharmacol Exp Ther
The principal aim of the study was to determine the influence of influenza A virus infection on capsaicin-induced relaxation responses in mouse isolated tracheal segments and clarify the underlying mechanisms. Anesthetized mice were intranasally inoculated with influenza A/PR-8/34 virus (VIRUS) or vehicle (SHAM), and 4 days later tracheal segme
3. The adenosine A1 receptor antagonist BIIP 20 counteracts scopolamine-induced behavioral deficits in the passive avoidance task in the rat.
Pitsikas N, Borsini F; Eur J Pharmacol
The present study investigated the effects of the putative adenosine A1 receptor antagonist BIIP 20 ((S)-(-)-8-(3-oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione) on counteracting scopolamine-induced behavioral deficits in the rat in the passive avoidance paradigm. A single oral application of BIIP 20 (1 and 3 mg/kg) 90 min before the rats re

Conclusion

The research literature on ((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione) demonstrates sustained scientific interest, with publications continuing through 0. The compound serves as an important building block in synthetic chemistry and has been explored for various applications. Researchers and industrial users can view detailed specifications or submit an inquiry for pricing and availability.

Data Sources: PubMed/MEDLINE, CrossRef. 3 papers analyzed. Last updated: 2026-05-25. This article is automatically generated from peer-reviewed research data.