![5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine structure](/static/products/100/1004643-49-5.webp)
5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine
TL;DR: 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine (CAS 1004643-49-5) is a chemical compound with molecular formula C12H12F3N3 and molecular weight 255.09833 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-methyl-1-[[3-(trifluoromethyl)phenyl]methyl]pyrazol-3-amine
Also Known As: 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine, 5-Methyl-1-{[3-(trifluoromethyl)phenyl]methyl}-1h-pyrazol-3-amine, 5-methyl-1-[[3-(trifluoromethyl)phenyl]methyl]pyrazol-3-amine, ethyl p-nitrophenyl l-trans-epoxysuccinate, 5-Methyl-1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-3-amine
Technical Specifications
| Molecular Formula | C12H12F3N3 |
| Molecular Weight | 255.09833 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 43.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 255.09833 Da |
| Heavy Atoms | 18 |
| Complexity | 282.0 |
| SMILES | CC1=CC(=NN1CC2=CC(=CC=C2)C(F)(F)F)N |
| InChIKey | GAYJVRYWRNUKOD-UHFFFAOYSA-N |
Chemical Property Profile of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine
Property Insights of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine. With a topological polar surface area (TPSA) of 43.8 Ų, 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine?
The CAS number of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine is 1004643-49-5.
What is the molecular formula of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine?
The molecular formula of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine is C12H12F3N3.
What is the molecular weight of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine?
The molecular weight of 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine is 255.09833 g/mol.
Where can I buy 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine?
You can request a quote for 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine?
Yes, CoreyChem provides custom synthesis services for 5-methyl-1-[3-(trifluoromethyl)benzyl]-1H-pyrazol-3-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.