TL;DR: F2743-0190 (CAS 1005300-00-4) is a chemical compound with molecular formula C20H16ClFN2O3 and molecular weight 386.08334 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(5-chloro-2-methoxyphenyl)-1-[(3-fluorophenyl)methyl]-2-oxopyridine-3-carboxamide
Also Known As: F2743-0190, N-(5-chloro-2-methoxyphenyl)-1-(3-fluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, N-(5-chloro-2-methoxyphenyl)-1-[(3-fluorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxamide, N-(5-chloro-2-methoxyphenyl)-1-[(3-fluorophenyl)methyl]-2-oxopyridine-3-carboxamide
| Molecular Formula | C20H16ClFN2O3 |
| Molecular Weight | 386.08334 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 58.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 386.08334 Da |
| Heavy Atoms | 27 |
| Complexity | 624.0 |
| SMILES | COC1=C(C=C(C=C1)Cl)NC(=O)C2=CC=CN(C2=O)CC3=CC(=CC=C3)F |
| InChIKey | UIWQQBHTMPZNNP-UHFFFAOYSA-N |
The XLogP value of 3.6 indicates that F2743-0190 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.6 Ų, F2743-0190 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F2743-0190 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of F2743-0190 is 1005300-00-4.
The molecular formula of F2743-0190 is C20H16ClFN2O3.
The molecular weight of F2743-0190 is 386.08334 g/mol.
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