N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide
TL;DR: N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide (CAS 1005587-77-8) is a chemical compound with molecular formula C10H7BrF2N4O and molecular weight 315.97714 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(5-bromo-2-pyridinyl)-1-(difluoromethyl)pyrazole-3-carboxamide
Also Known As: N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide, N-(5-BROMO-2-PYRIDYL)-1-(DIFLUOROMETHYL)-1H-PYRAZOLE-3-CARBOXAMIDE, N-(5-bromopyridin-2-yl)-1-(difluoromethyl)-1H-pyrazole-3-carboxamide
Technical Specifications
| Molecular Formula | C10H7BrF2N4O |
| Molecular Weight | 315.97714 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 59.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 315.97714 Da |
| Heavy Atoms | 18 |
| Complexity | 308.0 |
| SMILES | C1=CC(=NC=C1Br)NC(=O)C2=NN(C=C2)C(F)F |
| InChIKey | UZDLBXBLKRCPNH-UHFFFAOYSA-N |
Chemical Property Profile of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide
Property Insights of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide. With a topological polar surface area (TPSA) of 59.8 Ų, N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide?
The CAS number of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide is 1005587-77-8.
What is the molecular formula of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide?
The molecular formula of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide is C10H7BrF2N4O.
What is the molecular weight of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide?
The molecular weight of N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide is 315.97714 g/mol.
Where can I buy N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide?
You can request a quote for N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide?
Yes, CoreyChem provides custom synthesis services for N-(5-bromopyridin-2-yl)-1-(difluoromethyl)pyrazole-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.