N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide
TL;DR: N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide (CAS 1005588-91-9) is a chemical compound with molecular formula C10H7ClF2N4O and molecular weight 272.02765 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(5-chloro-2-pyridinyl)-2-(difluoromethyl)pyrazole-3-carboxamide
Also Known As: N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide, N-(5-chloropyridin-2-yl)-1-(difluoromethyl)-1H-pyrazole-5-carboxamide, N-(5-CHLORO-2-PYRIDYL)-1-(DIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE
Technical Specifications
| Molecular Formula | C10H7ClF2N4O |
| Molecular Weight | 272.02765 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 59.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 272.02765 Da |
| Heavy Atoms | 18 |
| Complexity | 308.0 |
| SMILES | C1=CC(=NC=C1Cl)NC(=O)C2=CC=NN2C(F)F |
| InChIKey | IDRMKJYPIIOCEG-UHFFFAOYSA-N |
Chemical Property Profile of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide
Property Insights of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide. With a topological polar surface area (TPSA) of 59.8 Ų, N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide?
The CAS number of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide is 1005588-91-9.
What is the molecular formula of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide?
The molecular formula of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide is C10H7ClF2N4O.
What is the molecular weight of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide?
The molecular weight of N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide is 272.02765 g/mol.
Where can I buy N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide?
You can request a quote for N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide?
Yes, CoreyChem provides custom synthesis services for N-(5-chloropyridin-2-yl)-2-(difluoromethyl)pyrazole-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.