![(4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone structure](/static/products/1005/1005640-72-1.webp)
(4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
TL;DR: (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone (CAS 1005640-72-1) is a chemical compound with molecular formula C17H18ClF3N4O and molecular weight 386.11212 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(4-chloro-1,3-dimethylpyrazol-5-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Also Known As: (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone, 4-chloro-1,3-dimethylpyrazol-5-yl 4-[3-(trifluoromethyl)phenyl]piperazinyl ket one, (4-chloro-1,3-dimethyl-1H-pyrazol-5-yl){4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}methanone, (4-CHLORO-1,3-DIMETHYL-1H-PYRAZOL-5-YL){4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO}METHANONE, (4-chloro-2,5-dimethyl-pyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Technical Specifications
| Molecular Formula | C17H18ClF3N4O |
| Molecular Weight | 386.11212 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 41.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 386.11212 Da |
| Heavy Atoms | 26 |
| Complexity | 513.0 |
| SMILES | CC1=NN(C(=C1Cl)C(=O)N2CCN(CC2)C3=CC=CC(=C3)C(F)(F)F)C |
| InChIKey | KKPVGYHKTXSYTA-UHFFFAOYSA-N |
Chemical Property Profile of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Property Insights of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
The XLogP value of 3.5 indicates that (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.4 Ų, (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone?
The CAS number of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone is 1005640-72-1.
What is the molecular formula of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone?
The molecular formula of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone is C17H18ClF3N4O.
What is the molecular weight of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone?
The molecular weight of (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone is 386.11212 g/mol.
Where can I buy (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone?
You can request a quote for (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone?
Yes, CoreyChem provides custom synthesis services for (4-chloro-2,5-dimethylpyrazol-3-yl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.