(E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate
TL;DR: (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate (CAS 1006003-19-5) is a chemical compound with molecular formula C15H12ClNO3S and molecular weight 321.02264 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl 2-[[(E)-3-(2-chlorophenyl)prop-2-enoyl]amino]thiophene-3-carboxylate
Also Known As: (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate, F1358-0128, methyl 2-[(2E)-3-(2-chlorophenyl)prop-2-enamido]thiophene-3-carboxylate, methyl 2-[[(E)-3-(2-chlorophenyl)prop-2-enoyl]amino]thiophene-3-carboxylate
Technical Specifications
| Molecular Formula | C15H12ClNO3S |
| Molecular Weight | 321.02264 g/mol |
| XLogP | 4.2 |
| Topological Polar Surface Area (TPSA) | 83.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 321.02264 Da |
| Heavy Atoms | 21 |
| Complexity | 416.0 |
| SMILES | COC(=O)C1=C(SC=C1)NC(=O)/C=C/C2=CC=CC=C2Cl |
| InChIKey | XQUAWZHXONOLSJ-VOTSOKGWSA-N |
Chemical Property Profile of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate
Property Insights of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate
The XLogP value of 4.2 indicates that (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate. Following Lipinski's Rule of Five, (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate?
The CAS number of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate is 1006003-19-5.
What is the molecular formula of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate?
The molecular formula of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate is C15H12ClNO3S.
What is the molecular weight of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate?
The molecular weight of (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate is 321.02264 g/mol.
Where can I buy (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate?
You can request a quote for (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate?
Yes, CoreyChem provides custom synthesis services for (E)-methyl 2-(3-(2-chlorophenyl)acrylamido)thiophene-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.