Ro 18-5364
TL;DR: Ro 18-5364 (CAS 101388-01-6) is a chemical compound with molecular formula C22H25N3O3S and molecular weight 411.16165 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[(4-methoxy-3-methyl-2-pyridinyl)methylsulfinyl]-5,5,7,7-tetramethyl-3H-cyclopenta[f]benzimidazol-6-one
Also Known As: Ro 18-5364, Ro-18-5364, 5,7-Dihydro-2-(((4-methoxy-3-methyl-2-pyridyl)methyl)sulfinyl)-5,5,7,7-tetramethylindeno(5,6-d)imidazol-6(1H)-one, 2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5,5,7,7-tetramethyl-3H-cyclopenta[f]benzimidazol-6-one, 2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-5,5,7,7-tetramethyl-5,7-dihydroindeno[5,6-d]imidazol-6(1H)-one
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H25N3O3S |
| Molecular Weight | 411.16165 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 104.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 411.16165 Da |
| Heavy Atoms | 29 |
| Complexity | 682.0 |
| SMILES | CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C4C(=C3)C(C(=O)C4(C)C)(C)C)OC |
| InChIKey | YBCJDBBYBFMVEG-UHFFFAOYSA-N |
Product Description
Applications: Ro 18-5364 is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Ro 18-5364 is a pharmaceutical intermediate identified by CAS number 101388-01-6 and the molecular formula C22H25N3O3S and a molecular weight of 411.16 g/mol. Synonyms include Ro 18-5364 and ACMC-20m4f5.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Ro 18-5364
Property Insights of Ro 18-5364
The XLogP value of 3.1 indicates that Ro 18-5364 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Ro 18-5364. Following Lipinski's Rule of Five, Ro 18-5364 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Ro 18-5364?
The CAS number of Ro 18-5364 is 101388-01-6.
What is the molecular formula of Ro 18-5364?
The molecular formula of Ro 18-5364 is C22H25N3O3S.
What is the molecular weight of Ro 18-5364?
The molecular weight of Ro 18-5364 is 411.16165 g/mol.
What are the applications of Ro 18-5364?
Ro 18-5364 is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Ro 18-5364?
You can request a quote for Ro 18-5364 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Ro 18-5364?
Yes, CoreyChem provides custom synthesis services for Ro 18-5364 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.