Lomerizine Hydrochloride
TL;DR: Lomerizine Hydrochloride (CAS 101477-54-7) is a chemical compound with molecular formula C27H32Cl2F2N2O3 and molecular weight 540.1758 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
Also Known As: Lomerizine dihydrochloride, Lomerizine hydrochloride, lomerizine, Lomerizine HCl, Terranas
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C27H32Cl2F2N2O3 |
| Molecular Weight | 540.1758 g/mol |
| XLogP | 5.74 |
| Topological Polar Surface Area (TPSA) | 34.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 540.1758 Da |
| Heavy Atoms | 36 |
| Complexity | 568.0 |
| SMILES | COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl |
| InChIKey | LOGVKVSFYBBUAJ-UHFFFAOYSA-N |
Chemical Property Profile of Lomerizine Hydrochloride
Property Insights of Lomerizine Hydrochloride
The XLogP value of 5.74 indicates that Lomerizine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.2 Ų, Lomerizine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lomerizine Hydrochloride has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Lomerizine Hydrochloride?
The CAS number of Lomerizine Hydrochloride is 101477-54-7.
What is the molecular formula of Lomerizine Hydrochloride?
The molecular formula of Lomerizine Hydrochloride is C27H32Cl2F2N2O3.
What is the molecular weight of Lomerizine Hydrochloride?
The molecular weight of Lomerizine Hydrochloride is 540.1758 g/mol.
Where can I buy Lomerizine Hydrochloride?
You can request a quote for Lomerizine Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lomerizine Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Lomerizine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.