Lomerizine
TL;DR: Lomerizine (CAS 101477-55-8) is a chemical compound with molecular formula C27H30F2N2O3 and molecular weight 468.22244 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine
Also Known As: lomerizine, lomerizina, Lomerizine [INN], iomerizine, lomerizinum
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C27H30F2N2O3 |
| Molecular Weight | 468.22244 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 34.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 468.22244 Da |
| Heavy Atoms | 34 |
| Complexity | 568.0 |
| SMILES | COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC |
| InChIKey | JQSAYKKFZOSZGJ-UHFFFAOYSA-N |
Product Description
Applications: Lomerizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Lomerizine is a pharmaceutical intermediate identified by CAS number 101477-55-8 and the molecular formula C27H30F2N2O3 and a molecular weight of 468.22 g/mol. Synonyms include lomerizine and lomerizina.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Lomerizine
Property Insights of Lomerizine
The XLogP value of 4.9 indicates that Lomerizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.2 Ų, Lomerizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lomerizine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Lomerizine?
The CAS number of Lomerizine is 101477-55-8.
What is the molecular formula of Lomerizine?
The molecular formula of Lomerizine is C27H30F2N2O3.
What is the molecular weight of Lomerizine?
The molecular weight of Lomerizine is 468.22244 g/mol.
What are the applications of Lomerizine?
Lomerizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Lomerizine?
You can request a quote for Lomerizine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lomerizine?
Yes, CoreyChem provides custom synthesis services for Lomerizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.