TL;DR: 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine (CAS 1021928-82-4) is a chemical compound with molecular formula C15H12N4S and molecular weight 280.07828 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-phenyl-N-[(E)-pyridin-2-ylmethylideneamino]-1,3-thiazol-2-amine
Also Known As: BAS 02003774, J2.486.789G, 2-[2-(2-Pyridinylmethylene)hydrazino]-4-phenylthiazole, 4-phenyl-N-[(E)-2-pyridylmethyleneamino]thiazol-2-amine, (E)-4-phenyl-2-(2-(pyridin-2-ylmethylene)hydrazinyl)thiazole
| Molecular Formula | C15H12N4S |
| Molecular Weight | 280.07828 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 78.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 280.07828 Da |
| Heavy Atoms | 20 |
| Complexity | 317.0 |
| SMILES | C1=CC=C(C=C1)C2=CSC(=N2)N/N=C/C3=CC=CC=N3 |
| InChIKey | JTHIWSXJCFHERN-LICLKQGHSA-N |
The XLogP value of 3.8 indicates that 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine. Following Lipinski's Rule of Five, 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is 1021928-82-4.
The molecular formula of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is C15H12N4S.
The molecular weight of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is 280.07828 g/mol.
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