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2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine structure
Fine Chemical

2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine

TL;DR: 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine (CAS 1021928-82-4) is a chemical compound with molecular formula C15H12N4S and molecular weight 280.07828 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

4-phenyl-N-[(E)-pyridin-2-ylmethylideneamino]-1,3-thiazol-2-amine

Also Known As: BAS 02003774, J2.486.789G, 2-[2-(2-Pyridinylmethylene)hydrazino]-4-phenylthiazole, 4-phenyl-N-[(E)-2-pyridylmethyleneamino]thiazol-2-amine, (E)-4-phenyl-2-(2-(pyridin-2-ylmethylene)hydrazinyl)thiazole

CAS Number
1021928-82-4
Molecular Formula
C15H12N4S
Molecular Weight
280.07828 g/mol
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Technical Specifications

Molecular FormulaC15H12N4S
Molecular Weight280.07828 g/mol
XLogP3.8
Topological Polar Surface Area (TPSA)78.4 Ų
Hydrogen Bond Donors1
Hydrogen Bond Acceptors5
Rotatable Bonds4
Exact Mass280.07828 Da
Heavy Atoms20
Complexity317.0
SMILESC1=CC=C(C=C1)C2=CSC(=N2)N/N=C/C3=CC=CC=N3
InChIKeyJTHIWSXJCFHERN-LICLKQGHSA-N

Chemical Property Profile of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine

XLogP
3.8
TPSA (Topological Polar Surface Area)
78.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
20
Complexity
317.0
Exact Mass
280.07828
Monoisotopic Mass
280.07828
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine

The XLogP value of 3.8 indicates that 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine. Following Lipinski's Rule of Five, 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the CAS number of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine?

The CAS number of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is 1021928-82-4.

What is the molecular formula of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine?

The molecular formula of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is C15H12N4S.

What is the molecular weight of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine?

The molecular weight of 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine is 280.07828 g/mol.

Where can I buy 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine?

You can request a quote for 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine?

Yes, CoreyChem provides custom synthesis services for 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}pyridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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