TL;DR: 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide (CAS 10224-03-0) is a chemical compound with molecular formula C16H14Cl2N2O3 and molecular weight 352.03815 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-N-[4-[4-[(2-chloroacetyl)amino]phenoxy]phenyl]acetamide
Also Known As: 2-CHLORO-N-(4-[4-(2-CHLORO-ACETYLAMINO)-PHENOXY]-PHENYL)-ACETAMIDE, 2-chloro-N-[4-[4-[(2-chloroacetyl)amino]phenoxy]phenyl]acetamide, Acetamide,N,N'-(oxydi-4,1-phenylene)bis[2-chloro- (9CI), N,N'-(Oxydi-4,1-phenylene)bis(2-chloroacetamide), N,N'-(Oxybis(4,1-phenylene))bis(2-chloroacetamide)
| Molecular Formula | C16H14Cl2N2O3 |
| Molecular Weight | 352.03815 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 67.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 352.03815 Da |
| Heavy Atoms | 23 |
| Complexity | 357.0 |
| SMILES | C1=CC(=CC=C1NC(=O)CCl)OC2=CC=C(C=C2)NC(=O)CCl |
| InChIKey | SEWAENFHTIIIGK-UHFFFAOYSA-N |
The XLogP value of 3.0 indicates that 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide. Following Lipinski's Rule of Five, 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide is 10224-03-0.
The molecular formula of 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide is C16H14Cl2N2O3.
The molecular weight of 2-Chloro-N-(4-[4-(2-chloro-acetylamino)-phenoxy]-phenyl)-acetamide is 352.03815 g/mol.
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