4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine
TL;DR: 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine (CAS 1023528-16-6) is a chemical compound with molecular formula C15H12ClN3S and molecular weight 301.04404 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine
Also Known As: (4-(4-CHLORO-3-METHYLPHENYL)(2,5-THIAZOLYL))-4-PYRIDYLAMINE, 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine, 4-(4-chloro-3-methyl-phenyl)-N-(4-pyridyl)thiazol-2-amine, 4-(4-Chloro-3-methylphenyl)-N-(pyridin-4-yl)thiazol-2-amine, N-[4-(4-chloro-3-methyl-phenyl)-1,3-thiazol-2-yl]pyridin-4-amine
Technical Specifications
| Molecular Formula | C15H12ClN3S |
| Molecular Weight | 301.04404 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 66.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 301.04404 Da |
| Heavy Atoms | 20 |
| Complexity | 311.0 |
| SMILES | CC1=C(C=CC(=C1)C2=CSC(=N2)NC3=CC=NC=C3)Cl |
| InChIKey | DLRJOYRBVZJEIC-UHFFFAOYSA-N |
Chemical Property Profile of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine
Property Insights of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine
The XLogP value of 4.4 indicates that 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine. Following Lipinski's Rule of Five, 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine?
The CAS number of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine is 1023528-16-6.
What is the molecular formula of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine?
The molecular formula of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine is C15H12ClN3S.
What is the molecular weight of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine?
The molecular weight of 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine is 301.04404 g/mol.
Where can I buy 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine?
You can request a quote for 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine?
Yes, CoreyChem provides custom synthesis services for 4-(4-chloro-3-methylphenyl)-N-pyridin-4-yl-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.