Maprotiline
TL;DR: Maprotiline (CAS 10262-69-8) is a chemical compound with molecular formula C20H23N and molecular weight 277.18304 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Also Known As: maprotiline, Maprotilina, Maprotylina, Maprotilinum, Dibencycladine
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H23N |
| Molecular Weight | 277.18304 g/mol |
| XLogP | 4.6 |
| Topological Polar Surface Area (TPSA) | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 4 |
| Exact Mass | 277.18304 Da |
| Heavy Atoms | 21 |
| Complexity | 339.0 |
| Melting Point | 93 |
| Solubility | Slightly soluble |
| SMILES | CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24 |
| InChIKey | QSLMDECMDJKHMQ-UHFFFAOYSA-N |
Chemical Property Profile of Maprotiline
Property Insights of Maprotiline
The XLogP value of 4.6 indicates that Maprotiline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, Maprotiline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Maprotiline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Maprotiline?
The CAS number of Maprotiline is 10262-69-8.
What is the molecular formula of Maprotiline?
The molecular formula of Maprotiline is C20H23N.
What is the molecular weight of Maprotiline?
The molecular weight of Maprotiline is 277.18304 g/mol.
Where can I buy Maprotiline?
You can request a quote for Maprotiline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Maprotiline?
Yes, CoreyChem provides custom synthesis services for Maprotiline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.