Clevudine
TL;DR: Clevudine (CAS 1027764-72-2) is a chemical compound with molecular formula C10H13FN2O5 and molecular weight 260.08084 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: Clevudine, 1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine, 1-(2-Fluoro-2-deoxy-alpha-L-arabinofuranosyl)thymine, 1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Technical Specifications
| Molecular Formula | C10H13FN2O5 |
| Molecular Weight | 260.08084 g/mol |
| XLogP | -0.9 |
| Topological Polar Surface Area (TPSA) | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 260.08084 Da |
| Heavy Atoms | 18 |
| Complexity | 413.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@H]([C@@H](O2)CO)O)F |
| InChIKey | GBBJCSTXCAQSSJ-VOQBNFLRSA-N |
Chemical Property Profile of Clevudine
Property Insights of Clevudine
The XLogP value of -0.9 indicates that Clevudine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Clevudine. Following Lipinski's Rule of Five, Clevudine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clevudine?
The CAS number of Clevudine is 1027764-72-2.
What is the molecular formula of Clevudine?
The molecular formula of Clevudine is C10H13FN2O5.
What is the molecular weight of Clevudine?
The molecular weight of Clevudine is 260.08084 g/mol.
Where can I buy Clevudine?
You can request a quote for Clevudine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clevudine?
Yes, CoreyChem provides custom synthesis services for Clevudine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.