Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine
TL;DR: Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine (CAS 1028127-71-0) is a chemical compound with molecular formula C15H11ClF3N3 and molecular weight 325.05936 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine;hydrochloride
Also Known As: Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine, quinazolin-4-yl[3-(trifluoromethyl)phenyl]amine, chloride, N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine hydrochloride, N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine hydrochloride, N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine;hydrochloride
Technical Specifications
| Molecular Formula | C15H11ClF3N3 |
| Molecular Weight | 325.05936 g/mol |
| XLogP | 4.814 |
| Topological Polar Surface Area (TPSA) | 37.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 325.05936 Da |
| Heavy Atoms | 22 |
| Complexity | 348.0 |
| SMILES | C1=CC=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C(F)(F)F.Cl |
| InChIKey | HRBLUGZRNSNMAX-UHFFFAOYSA-N |
Chemical Property Profile of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine
Property Insights of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine
The XLogP value of 4.814 indicates that Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.8 Ų, Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine?
The CAS number of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine is 1028127-71-0.
What is the molecular formula of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine?
The molecular formula of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine is C15H11ClF3N3.
What is the molecular weight of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine?
The molecular weight of Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine is 325.05936 g/mol.
Where can I buy Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine?
You can request a quote for Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine?
Yes, CoreyChem provides custom synthesis services for Quinazolin-4-yl-(3-trifluoromethyl-phenyl)-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.