Phenylacetyl chloride
TL;DR: Phenylacetyl chloride (CAS 103-80-0) is a chemical compound with molecular formula C8H7ClO and molecular weight 154.01854 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-phenylacetyl chloride
Also Known As: PHENYLACETYL CHLORIDE, Benzeneacetyl chloride, 2-phenylacetyl chloride, phenyl acetyl chloride, Phenacetyl chloride
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H7ClO |
| Molecular Weight | 154.01854 g/mol |
| XLogP | 2.4 |
| Topological Polar Surface Area (TPSA) | 17.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 154.01854 Da |
| Heavy Atoms | 10 |
| Complexity | 116.0 |
| SMILES | C1=CC=C(C=C1)CC(=O)Cl |
| InChIKey | VMZCDNSFRSVYKQ-UHFFFAOYSA-N |
Product Description
Applications: Phenylacetyl chloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Phenylacetyl chloride (CAS 103-80-0) is a heterocyclic building block with the molecular formula C8H7ClO and a molecular weight of 154.02 g/mol. Synonyms include PHENYLACETYL CHLORIDE and Benzeneacetyl chloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Phenylacetyl chloride
Property Insights of Phenylacetyl chloride
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Phenylacetyl chloride. With a topological polar surface area (TPSA) of 17.1 Ų, Phenylacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Phenylacetyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Phenylacetyl chloride?
The CAS number of Phenylacetyl chloride is 103-80-0.
What is the molecular formula of Phenylacetyl chloride?
The molecular formula of Phenylacetyl chloride is C8H7ClO.
What is the molecular weight of Phenylacetyl chloride?
The molecular weight of Phenylacetyl chloride is 154.01854 g/mol.
What are the applications of Phenylacetyl chloride?
Phenylacetyl chloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Phenylacetyl chloride?
You can request a quote for Phenylacetyl chloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Phenylacetyl chloride?
Yes, CoreyChem provides custom synthesis services for Phenylacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.