Fasudil
TL;DR: Fasudil (CAS 103745-39-7) is a chemical compound with molecular formula C14H17N3O2S and molecular weight 291.10416 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
Also Known As: Fasudil, Fasudil hydrochloride, Fasudilum, Fasudil [INN], Eril
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H17N3O2S |
| Molecular Weight | 291.10416 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 70.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 291.10416 Da |
| Heavy Atoms | 20 |
| Complexity | 421.0 |
| SMILES | C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
| InChIKey | NGOGFTYYXHNFQH-UHFFFAOYSA-N |
Product Description
Applications: Fasudil is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Fasudil (CAS 103745-39-7) has the molecular formula C14H17N3O2S and a molecular weight of 291.1 g/mol. Synonyms include Fasudil and Fasudil hydrochloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Fasudil
Property Insights of Fasudil
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Fasudil. The TPSA of 70.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Fasudil. Following Lipinski's Rule of Five, Fasudil has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Fasudil?
The CAS number of Fasudil is 103745-39-7.
What is the molecular formula of Fasudil?
The molecular formula of Fasudil is C14H17N3O2S.
What is the molecular weight of Fasudil?
The molecular weight of Fasudil is 291.10416 g/mol.
What are the applications of Fasudil?
Fasudil is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis...
Where can I buy Fasudil?
You can request a quote for Fasudil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Fasudil?
Yes, CoreyChem provides custom synthesis services for Fasudil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.