2'-Dfdap
TL;DR: 2'-Dfdap (CAS 103828-81-5) is a chemical compound with molecular formula C10H12F2N6O3 and molecular weight 302.0939 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,3R)-5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol
Also Known As: 2'-Dfdap, LY 207702, 2',2'-Difluorodeoxyribofuranosyl-2,6-diaminopurine, 9-(2-Deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-9H-purine-2,6-diamine, (2R,3R)-5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol
Technical Specifications
| Molecular Formula | C10H12F2N6O3 |
| Molecular Weight | 302.0939 g/mol |
| XLogP | -1.1 |
| Topological Polar Surface Area (TPSA) | 156.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 2 |
| Exact Mass | 302.0939 Da |
| Heavy Atoms | 21 |
| Complexity | 405.0 |
| SMILES | C([C@@H]1[C@H](C(C(O1)C2=NC3=NC(=NC(=C3N2)N)N)(F)F)O)O |
| InChIKey | UPHLSICWROERBL-CUAOIRRQSA-N |
Chemical Property Profile of 2'-Dfdap
Property Insights of 2'-Dfdap
The XLogP value of -1.1 indicates that 2'-Dfdap is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 156.0 Ų indicates high polarity, suggesting 2'-Dfdap may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2'-Dfdap has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2'-Dfdap?
The CAS number of 2'-Dfdap is 103828-81-5.
What is the molecular formula of 2'-Dfdap?
The molecular formula of 2'-Dfdap is C10H12F2N6O3.
What is the molecular weight of 2'-Dfdap?
The molecular weight of 2'-Dfdap is 302.0939 g/mol.
Where can I buy 2'-Dfdap?
You can request a quote for 2'-Dfdap directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2'-Dfdap?
Yes, CoreyChem provides custom synthesis services for 2'-Dfdap and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.