Lacidipine
TL;DR: Lacidipine (CAS 103890-78-4) is a chemical compound with molecular formula C26H33NO6 and molecular weight 455.23077 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
diethyl 2,6-dimethyl-4-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Lacidipine, Cislacidipine, cis Lacidipine, trans Lacidipine, diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C26H33NO6 |
| Molecular Weight | 455.23077 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 90.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 11 |
| Exact Mass | 455.23077 Da |
| Heavy Atoms | 33 |
| Complexity | 805.0 |
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C=CC(=O)OC(C)(C)C)C(=O)OCC)C)C |
| InChIKey | GKQPCPXONLDCMU-UHFFFAOYSA-N |
Chemical Property Profile of Lacidipine
Property Insights of Lacidipine
The XLogP value of 4.5 indicates that Lacidipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Lacidipine. Following Lipinski's Rule of Five, Lacidipine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Lacidipine?
The CAS number of Lacidipine is 103890-78-4.
What is the molecular formula of Lacidipine?
The molecular formula of Lacidipine is C26H33NO6.
What is the molecular weight of Lacidipine?
The molecular weight of Lacidipine is 455.23077 g/mol.
Where can I buy Lacidipine?
You can request a quote for Lacidipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lacidipine?
Yes, CoreyChem provides custom synthesis services for Lacidipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.