(4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)
TL;DR: (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) (CAS 1049733-67-6) is a chemical compound with molecular formula C12H15Cl2NO2 and molecular weight 275.04797 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S,4R)-4-[(2-chlorophenyl)methyl]pyrrolidine-2-carboxylic acid;hydrochloride
Also Known As: (2S,4R)-4-(2-Chlorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride, (R)-gamma-(2-chloro-benzyl)-L-proline-HCl, H-Pro{4-Bzl(2-Cl)}-OH HCl, 1116AA, (2S,4R)-4-[(2-chlorophenyl)methyl]pyrrolidine-2-carboxylic acid;hydrochloride
Technical Specifications
| Molecular Formula | C12H15Cl2NO2 |
| Molecular Weight | 275.04797 g/mol |
| XLogP | 2.367 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 275.04797 Da |
| Heavy Atoms | 17 |
| Complexity | 259.0 |
| SMILES | C1[C@H](CN[C@@H]1C(=O)O)CC2=CC=CC=C2Cl.Cl |
| InChIKey | QVOBVSIKQJKMMO-NINOIYOQSA-N |
Chemical Property Profile of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)
Property Insights of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)
The XLogP value of 2.367 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1). With a topological polar surface area (TPSA) of 49.3 Ų, (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)?
The CAS number of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) is 1049733-67-6.
What is the molecular formula of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)?
The molecular formula of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) is C12H15Cl2NO2.
What is the molecular weight of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)?
The molecular weight of (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) is 275.04797 g/mol.
Where can I buy (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)?
You can request a quote for (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1)?
Yes, CoreyChem provides custom synthesis services for (4R)-4-((2-Chlorophenyl)methyl)-L-proline--hydrogen chloride (1/1) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.