(4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)
TL;DR: (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) (CAS 1049743-68-1) is a chemical compound with molecular formula C13H15ClF3NO2 and molecular weight 309.07434 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S,4R)-4-[[4-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxylic acid;hydrochloride
Also Known As: (2S,4R)-4-(4-(Trifluoromethyl)benzyl)pyrrolidine-2-carboxylic acid hydrochloride, PS-1145 dihydrochloride, 1147AA, H-Pro{4-Bzl(4-CF3)}-OH HCl, (R)-gamma-(4-Trifluoromethyl-benzyl)-L-proline-HCl
Technical Specifications
| Molecular Formula | C13H15ClF3NO2 |
| Molecular Weight | 309.07434 g/mol |
| XLogP | 2.7324 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 309.07434 Da |
| Heavy Atoms | 20 |
| Complexity | 324.0 |
| SMILES | C1[C@H](CN[C@@H]1C(=O)O)CC2=CC=C(C=C2)C(F)(F)F.Cl |
| InChIKey | LZNHALZTDTVONZ-XQKZEKTMSA-N |
Chemical Property Profile of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)
Property Insights of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)
The XLogP value of 2.7324 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1). With a topological polar surface area (TPSA) of 49.3 Ų, (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)?
The CAS number of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) is 1049743-68-1.
What is the molecular formula of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)?
The molecular formula of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) is C13H15ClF3NO2.
What is the molecular weight of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)?
The molecular weight of (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) is 309.07434 g/mol.
Where can I buy (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)?
You can request a quote for (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1)?
Yes, CoreyChem provides custom synthesis services for (4R)-4-((4-(Trifluoromethyl)phenyl)methyl)-L-proline--hydrogen chloride (1/1) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.