![(Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate structure](/static/products/105/1052527-35-1.webp)
(Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate
TL;DR: (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate (CAS 1052527-35-1) is a chemical compound with molecular formula C23H24ClF3N4O2 and molecular weight 480.154 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3Z)-3-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one;hydrate;hydrochloride
Also Known As: (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate, (3Z)-3-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methylidene]-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one hydrate hydrochloride
Technical Specifications
| Molecular Formula | C23H24ClF3N4O2 |
| Molecular Weight | 480.154 g/mol |
| XLogP | 3.5792 |
| Topological Polar Surface Area (TPSA) | 40.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 480.154 Da |
| Heavy Atoms | 33 |
| Complexity | 756.0 |
| SMILES | C\1CN2C(=NC3=CC=CC=C3C2=O)/C1=C\N4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F.O.Cl |
| InChIKey | VAZCMQCDQRBKEW-NDXGFPCWSA-N |
Chemical Property Profile of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate
Property Insights of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate
The XLogP value of 3.5792 indicates that (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.2 Ų, (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate?
The CAS number of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate is 1052527-35-1.
What is the molecular formula of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate?
The molecular formula of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate is C23H24ClF3N4O2.
What is the molecular weight of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate?
The molecular weight of (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate is 480.154 g/mol.
Where can I buy (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate?
You can request a quote for (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate?
Yes, CoreyChem provides custom synthesis services for (Z)-3-((4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one hydrochloride hydrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.