5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one
TL;DR: 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one (CAS 105277-03-0) is a chemical compound with molecular formula C10H7N5O and molecular weight 213.06506 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(1,2,4-triazol-1-yl)-1H-1,6-naphthyridin-2-one
Also Known As: 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one, 1,6-Naphthyridin-2(1H)-one, 5-(1H-1,2,4-triazol-1-yl)-, 5-(1,2,4-triazol-1-yl)-1H-1,6-naphthyridin-2-one, 5-(1H-1,2,4-triazol-1-yl)-1,2-dihydro-1,6-naphthyridin-2-one
Technical Specifications
| Molecular Formula | C10H7N5O |
| Molecular Weight | 213.06506 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 72.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 213.06506 Da |
| Heavy Atoms | 16 |
| Complexity | 318.0 |
| SMILES | C1=CC(=O)NC2=C1C(=NC=C2)N3C=NC=N3 |
| InChIKey | CLSUCOYKBIKURC-UHFFFAOYSA-N |
Chemical Property Profile of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one
Property Insights of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one. The TPSA of 72.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one. Following Lipinski's Rule of Five, 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one?
The CAS number of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one is 105277-03-0.
What is the molecular formula of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one?
The molecular formula of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one is C10H7N5O.
What is the molecular weight of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one?
The molecular weight of 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one is 213.06506 g/mol.
Where can I buy 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one?
You can request a quote for 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one?
Yes, CoreyChem provides custom synthesis services for 5-(1H-1,2,4-triazol-1-yl)-1,6-naphthyridin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.