4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine
TL;DR: 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine (CAS 105512-79-6) is a chemical compound with molecular formula C10H7F3N2S and molecular weight 244.0282 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine
Also Known As: 4-(4-Trifluoromethylphenyl)thiazol-2-ylamine, 4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine, thiazol-2-amine, 5, 2-Thiazolamine, 4-[4-(trifluoromethyl)phenyl]-, 4-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOL-2-AMINE
Technical Specifications
| Molecular Formula | C10H7F3N2S |
| Molecular Weight | 244.0282 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 67.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.0282 Da |
| Heavy Atoms | 16 |
| Complexity | 239.0 |
| SMILES | C1=CC(=CC=C1C2=CSC(=N2)N)C(F)(F)F |
| InChIKey | HYAHAIVZFRFEBU-UHFFFAOYSA-N |
Chemical Property Profile of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine
Property Insights of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine
The XLogP value of 3.2 indicates that 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine. Following Lipinski's Rule of Five, 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine?
The CAS number of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine is 105512-79-6.
What is the molecular formula of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine?
The molecular formula of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine is C10H7F3N2S.
What is the molecular weight of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine?
The molecular weight of 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine is 244.0282 g/mol.
Where can I buy 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine?
You can request a quote for 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine?
Yes, CoreyChem provides custom synthesis services for 4-(4-(Trifluoromethyl)phenyl)-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.