N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide
TL;DR: N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide (CAS 105878-40-8) is a chemical compound with molecular formula C8H7Cl3N2O2 and molecular weight 267.9573 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2,2,2-trichloro-1-hydroxyethyl)pyridine-3-carboxamide
Also Known As: N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide, NCIOpen2_002357, N-(2,2,2-trichloro-1-hydroxyethyl)pyridine-3-carboxamide, N-(1-hydroxy-2,2,2-trichloroethyl)nicotinamide, 3-pyridyl-N-(2,2,2-trichloro-1-hydroxyethyl)carboxamide
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H7Cl3N2O2 |
| Molecular Weight | 267.9573 g/mol |
| XLogP | 1.1 |
| Topological Polar Surface Area (TPSA) | 62.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 267.9573 Da |
| Heavy Atoms | 15 |
| Complexity | 232.0 |
| SMILES | C1=CC(=CN=C1)C(=O)NC(C(Cl)(Cl)Cl)O |
| InChIKey | MRIKZTIOXMGKPT-UHFFFAOYSA-N |
Chemical Property Profile of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide
Property Insights of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide
The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide. The TPSA of 62.2 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide. Following Lipinski's Rule of Five, N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide?
The CAS number of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide is 105878-40-8.
What is the molecular formula of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide?
The molecular formula of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide is C8H7Cl3N2O2.
What is the molecular weight of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide?
The molecular weight of N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide is 267.9573 g/mol.
Where can I buy N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide?
You can request a quote for N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide?
Yes, CoreyChem provides custom synthesis services for N-(2,2,2-trichloro-1-hydroxyethyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.