Tafenoquine
TL;DR: Tafenoquine (CAS 106635-80-7) is a chemical compound with molecular formula C24H28F3N3O3 and molecular weight 463.20828 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-N-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine
Also Known As: Tafenoquine, Etaquine, tafenoquina, Krintafel, Arakoda
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C24H28F3N3O3 |
| Molecular Weight | 463.20828 g/mol |
| XLogP | 5.4 |
| Topological Polar Surface Area (TPSA) | 78.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 9 |
| Exact Mass | 463.20828 Da |
| Heavy Atoms | 33 |
| Complexity | 597.0 |
| Solubility | Insoluble |
| SMILES | CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC |
| InChIKey | LBHLFPGPEGDCJG-UHFFFAOYSA-N |
Chemical Property Profile of Tafenoquine
Property Insights of Tafenoquine
The XLogP value of 5.4 indicates that Tafenoquine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Tafenoquine. Following Lipinski's Rule of Five, Tafenoquine has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Tafenoquine?
The CAS number of Tafenoquine is 106635-80-7.
What is the molecular formula of Tafenoquine?
The molecular formula of Tafenoquine is C24H28F3N3O3.
What is the molecular weight of Tafenoquine?
The molecular weight of Tafenoquine is 463.20828 g/mol.
Where can I buy Tafenoquine?
You can request a quote for Tafenoquine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tafenoquine?
Yes, CoreyChem provides custom synthesis services for Tafenoquine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.