Sibutramine
TL;DR: Sibutramine (CAS 106650-56-0) is a chemical compound with molecular formula C17H26ClN and molecular weight 279.17538 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine
Also Known As: sibutramine, Medaria, Meridia, Sibutraminum, Sibutramina
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H26ClN |
| Molecular Weight | 279.17538 g/mol |
| XLogP | 5.4 |
| Topological Polar Surface Area (TPSA) | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 279.17538 Da |
| Heavy Atoms | 19 |
| Complexity | 275.0 |
| Melting Point | 191-192 °C |
| Solubility | 2.9 |
| SMILES | CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C |
| InChIKey | UNAANXDKBXWMLN-UHFFFAOYSA-N |
Chemical Property Profile of Sibutramine
Property Insights of Sibutramine
The XLogP value of 5.4 indicates that Sibutramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, Sibutramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sibutramine has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Sibutramine?
The CAS number of Sibutramine is 106650-56-0.
What is the molecular formula of Sibutramine?
The molecular formula of Sibutramine is C17H26ClN.
What is the molecular weight of Sibutramine?
The molecular weight of Sibutramine is 279.17538 g/mol.
Where can I buy Sibutramine?
You can request a quote for Sibutramine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sibutramine?
Yes, CoreyChem provides custom synthesis services for Sibutramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.