Sibutramine
TL;DR: Sibutramine (CAS 106650-56-0) is a chemical compound with molecular formula C17H26ClN and molecular weight 279.17538 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine
Also Known As: sibutramine, Medaria, Meridia, Sibutraminum, Sibutramina
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H26ClN |
| Molecular Weight | 279.17538 g/mol |
| XLogP | 5.4 |
| Topological Polar Surface Area (TPSA) | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 279.17538 Da |
| Heavy Atoms | 19 |
| Complexity | 275.0 |
| Melting Point | 191-192 °C |
| Solubility | 2.9 |
| SMILES | CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C |
| InChIKey | UNAANXDKBXWMLN-UHFFFAOYSA-N |
Product Description
Applications: Sibutramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sibutramine (CAS 106650-56-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Sibutramine (CAS 106650-56-0) is a pharmaceutical intermediate with the molecular formula C17H26ClN and a molecular weight of 279.18 g/mol. Key physical properties include a solubility: 2.9. It is also known as sibutramine and Medaria.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Sibutramine
Property Insights of Sibutramine
The XLogP value of 5.4 indicates that Sibutramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, Sibutramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sibutramine has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Sibutramine?
The CAS number of Sibutramine is 106650-56-0.
What is the molecular formula of Sibutramine?
The molecular formula of Sibutramine is C17H26ClN.
What is the molecular weight of Sibutramine?
The molecular weight of Sibutramine is 279.17538 g/mol.
What are the applications of Sibutramine?
Sibutramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sibutramine (CAS 106650-56-0) with custom...
Where can I buy Sibutramine?
You can request a quote for Sibutramine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sibutramine?
Yes, CoreyChem provides custom synthesis services for Sibutramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.