Zafirlukast
TL;DR: Zafirlukast (CAS 107753-78-6) is a chemical compound with molecular formula C31H33N3O6S and molecular weight 575.209 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
cyclopentyl N-[3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methylindol-5-yl]carbamate
Also Known As: zafirlukast, Accolate, Olmoran, Aeronix, Accoleit
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C31H33N3O6S |
| Molecular Weight | 575.209 g/mol |
| XLogP | 5.5 |
| Topological Polar Surface Area (TPSA) | 124.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 575.209 Da |
| Heavy Atoms | 41 |
| Complexity | 1010.0 |
| Melting Point | 139 |
| Solubility | 9.62e-04 g/L |
| SMILES | CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC |
| InChIKey | YEEZWCHGZNKEEK-UHFFFAOYSA-N |
Chemical Property Profile of Zafirlukast
Property Insights of Zafirlukast
The XLogP value of 5.5 indicates that Zafirlukast is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 124.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Zafirlukast. Following Lipinski's Rule of Five, Zafirlukast has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Zafirlukast?
The CAS number of Zafirlukast is 107753-78-6.
What is the molecular formula of Zafirlukast?
The molecular formula of Zafirlukast is C31H33N3O6S.
What is the molecular weight of Zafirlukast?
The molecular weight of Zafirlukast is 575.209 g/mol.
Where can I buy Zafirlukast?
You can request a quote for Zafirlukast directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Zafirlukast?
Yes, CoreyChem provides custom synthesis services for Zafirlukast and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.