1-Bromo-3-chlorobenzene
TL;DR: 1-Bromo-3-chlorobenzene (CAS 108-37-2) is a chemical compound with molecular formula C6H4BrCl and molecular weight 189.91849 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-bromo-3-chlorobenzene
Also Known As: 1-Bromo-3-chlorobenzene, 3-BROMOCHLOROBENZENE, m-Bromochlorobenzene, 3-Chlorobromobenzene, m-Chlorobromobenzene
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4BrCl |
| Molecular Weight | 189.91849 g/mol |
| XLogP | 3.7 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 0 |
| Rotatable Bonds | 0 |
| Exact Mass | 189.91849 Da |
| Heavy Atoms | 8 |
| Complexity | 74.0 |
| Melting Point | -21.5 °C |
| Boiling Point | 196 °C @760 [mm Hg] |
| Density | 1.6302 @ 20°C |
| SMILES | C1=CC(=CC(=C1)Br)Cl |
| InChIKey | JRGGUPZKKTVKOV-UHFFFAOYSA-N |
Product Description
Applications: 1-Bromo-3-chlorobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1-Bromo-3-chlorobenzene (CAS 108-37-2) is a heterocyclic building block with the molecular formula C6H4BrCl and a molecular weight of 189.92 g/mol. Key physical properties include a density of 1.6302 @ 20°C g/cm³. Synonyms include 1-Bromo-3-chlorobenzene and 3-BROMOCHLOROBENZENE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Bromo-3-chlorobenzene
Property Insights of 1-Bromo-3-chlorobenzene
The XLogP value of 3.7 indicates that 1-Bromo-3-chlorobenzene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 0.0 Ų, 1-Bromo-3-chlorobenzene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Bromo-3-chlorobenzene has 0 hydrogen bond donor(s) and 0 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Bromo-3-chlorobenzene?
The CAS number of 1-Bromo-3-chlorobenzene is 108-37-2.
What is the molecular formula of 1-Bromo-3-chlorobenzene?
The molecular formula of 1-Bromo-3-chlorobenzene is C6H4BrCl.
What is the molecular weight of 1-Bromo-3-chlorobenzene?
The molecular weight of 1-Bromo-3-chlorobenzene is 189.91849 g/mol.
What are the applications of 1-Bromo-3-chlorobenzene?
1-Bromo-3-chlorobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 1-Bromo-3-chlorobenzene?
You can request a quote for 1-Bromo-3-chlorobenzene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Bromo-3-chlorobenzene?
Yes, CoreyChem provides custom synthesis services for 1-Bromo-3-chlorobenzene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.