Lapatinib
TL;DR: Lapatinib (CAS 1092929-10-6) is a chemical compound with molecular formula C29H26ClFN4O4S and molecular weight 580.1347 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Also Known As: Lapatinib, Tykerb, Lapatinib Ditosylate, Tyverb, Tycerb
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C29H26ClFN4O4S |
| Molecular Weight | 580.1347 g/mol |
| XLogP | 5.1 |
| Topological Polar Surface Area (TPSA) | 115.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 11 |
| Exact Mass | 580.1347 Da |
| Heavy Atoms | 40 |
| Complexity | 898.0 |
| SMILES | CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl |
| InChIKey | BCFGMOOMADDAQU-UHFFFAOYSA-N |
Chemical Property Profile of Lapatinib
Property Insights of Lapatinib
The XLogP value of 5.1 indicates that Lapatinib is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Lapatinib. Following Lipinski's Rule of Five, Lapatinib has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Lapatinib?
The CAS number of Lapatinib is 1092929-10-6.
What is the molecular formula of Lapatinib?
The molecular formula of Lapatinib is C29H26ClFN4O4S.
What is the molecular weight of Lapatinib?
The molecular weight of Lapatinib is 580.1347 g/mol.
Where can I buy Lapatinib?
You can request a quote for Lapatinib directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lapatinib?
Yes, CoreyChem provides custom synthesis services for Lapatinib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.