Tetrahydrothiophene
TL;DR: Tetrahydrothiophene (CAS 110-01-0) is a chemical compound with molecular formula C4H8S and molecular weight 88.03467 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
thiolane
Also Known As: tetrahydrothiophene, Thiolane, Thiophane, Thiacyclopentane, Thiophene, tetrahydro-
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H8S |
| Molecular Weight | 88.03467 g/mol |
| XLogP | 1.4 |
| Topological Polar Surface Area (TPSA) | 25.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 88.03467 Da |
| Heavy Atoms | 5 |
| Complexity | 22.0 |
| Melting Point | -96.16 °C |
| Boiling Point | 121.12 °C @ 760 MM HG |
| Density | 0.9987 @ 20 °C/4 °C |
| Flash Point | 55 °F (12 °C) |
| Vapor Pressure | 18.4 [mmHg] |
| Refractive Index | MAXIMUM ABSORPTION (ALCOHOL): 240 NM SHOULDER (LOG E= 1.7); INDEX OF REFRACTION: 1.5048 @ 20 °C/D; SADTLER REFERENCE NUMBER 133 (NMR, JEOL, 100 MC SPECTRA) |
| Solubility | INSOLUBLE IN WATER; SOL IN ALL PROPORTIONS IN ALCOHOL, ETHER, ACETONE, BENZENE, IN ORGANIC SOLVENTS |
| SMILES | C1CCSC1 |
| InChIKey | RAOIDOHSFRTOEL-UHFFFAOYSA-N |
Product Description
Applications: Tetrahydrothiophene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Tetrahydrothiophene (CAS 110-01-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Tetrahydrothiophene (CAS 110-01-0) is a heterocyclic building block with the molecular formula C4H8S and a molecular weight of 88.03 g/mol. Key physical properties include a density of 0.9987 @ 20 °C/4 °C g/cm³, a solubility: INSOLUBLE IN WATER; SOL IN ALL PROPORTIONS IN ALCOHOL, ETHER, ACETONE, BENZENE, IN ORGANIC SOLVENTS. It is also known as tetrahydrothiophene and Thiolane.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tetrahydrothiophene
Property Insights of Tetrahydrothiophene
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tetrahydrothiophene. With a topological polar surface area (TPSA) of 25.3 Ų, Tetrahydrothiophene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tetrahydrothiophene has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tetrahydrothiophene?
The CAS number of Tetrahydrothiophene is 110-01-0.
What is the molecular formula of Tetrahydrothiophene?
The molecular formula of Tetrahydrothiophene is C4H8S.
What is the molecular weight of Tetrahydrothiophene?
The molecular weight of Tetrahydrothiophene is 88.03467 g/mol.
What are the applications of Tetrahydrothiophene?
Tetrahydrothiophene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Tetrahydrothiophene (CAS 110-01-0)...
Where can I buy Tetrahydrothiophene?
You can request a quote for Tetrahydrothiophene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tetrahydrothiophene?
Yes, CoreyChem provides custom synthesis services for Tetrahydrothiophene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.