Piperazine
TL;DR: Piperazine (CAS 110-85-0) is a chemical compound with molecular formula C4H10N2 and molecular weight 86.0844 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
piperazine
Also Known As: piperazine, Diethylenediamine, Piperazidine, Piperazin, Antiren
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H10N2 |
| Molecular Weight | 86.0844 g/mol |
| XLogP | -1.5 |
| Topological Polar Surface Area (TPSA) | 24.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 86.0844 Da |
| Heavy Atoms | 6 |
| Complexity | 26.0 |
| Melting Point | 223 °F (NTP, 1992) |
| Boiling Point | 295 °F at 760 mmHg (NTP, 1992) |
| Density | 1.1 at 68 °F (NTP, 1992) - Denser than water; will sink |
| Flash Point | 190 °F (NTP, 1992) |
| Vapor Pressure | 0.16 [mmHg] |
| Refractive Index | Index of refraction = 1.446 at 113 °C |
| Solubility | Very soluble (NTP, 1992) |
| SMILES | C1CNCCN1 |
| InChIKey | GLUUGHFHXGJENI-UHFFFAOYSA-N |
Product Description
Applications: Piperazine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Piperazine (CAS 110-85-0) is a heterocyclic building block with the molecular formula C4H10N2 and a molecular weight of 86.08 g/mol. Key physical properties include a density of 1.1 at 68 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: Very soluble (NTP, 1992). Synonyms include piperazine and Diethylenediamine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Piperazine
Property Insights of Piperazine
The XLogP value of -1.5 indicates that Piperazine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 24.1 Ų, Piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Piperazine has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Piperazine?
The CAS number of Piperazine is 110-85-0.
What is the molecular formula of Piperazine?
The molecular formula of Piperazine is C4H10N2.
What is the molecular weight of Piperazine?
The molecular weight of Piperazine is 86.0844 g/mol.
What are the applications of Piperazine?
Piperazine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Piperazine?
You can request a quote for Piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Piperazine?
Yes, CoreyChem provides custom synthesis services for Piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.