TL;DR: Lodenosine (CAS 110143-10-7) is a chemical compound with molecular formula C10H12FN5O2 and molecular weight 253.0975 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(2S,4S,5R)-5-(6-aminopurin-9-yl)-4-fluorooxolan-2-yl]methanol
Also Known As: Lodenosine, FddA, F-ddA, Lodenosina, Lodensine
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C10H12FN5O2 |
| Molecular Weight | 253.0975 g/mol |
| XLogP | -0.2 |
| Topological Polar Surface Area (TPSA) | 99.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 253.0975 Da |
| Heavy Atoms | 18 |
| Complexity | 310.0 |
| SMILES | C1[C@H](O[C@H]([C@H]1F)N2C=NC3=C(N=CN=C32)N)CO |
| InChIKey | KBEMFSMODRNJHE-JFWOZONXSA-N |
The XLogP value of -0.2 indicates that Lodenosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Lodenosine. Following Lipinski's Rule of Five, Lodenosine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of Lodenosine is 110143-10-7.
The molecular formula of Lodenosine is C10H12FN5O2.
The molecular weight of Lodenosine is 253.0975 g/mol.
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