Bis(2-chloroethoxy)methane
TL;DR: Bis(2-chloroethoxy)methane (CAS 111-91-1) is a chemical compound with molecular formula C5H10Cl2O2 and molecular weight 172.00578 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-chloro-2-(2-chloroethoxymethoxy)ethane
Also Known As: BIS(2-CHLOROETHOXY)METHANE, Dichloroethylformal, Dichloroethyl formal, 2,2-Dichloroethylformal, Di-2-chloroethyl formal
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H10Cl2O2 |
| Molecular Weight | 172.00578 g/mol |
| XLogP | 1.2 |
| Topological Polar Surface Area (TPSA) | 18.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 172.00578 Da |
| Heavy Atoms | 9 |
| Complexity | 46.0 |
| Melting Point | Freezing point= -32.8 °C |
| Boiling Point | 424.6 °F at 760 mmHg (NTP, 1992) |
| Density | 1.2339 @ 20 °C/20 °C |
| Flash Point | 230 °F (NTP, 1992) |
| Vapor Pressure | 0.13 [mmHg] |
| Solubility | ... Miscible with most organic solvents. |
| SMILES | C(CCl)OCOCCCl |
| InChIKey | NLXGURFLBLRZRO-UHFFFAOYSA-N |
Product Description
Applications: Bis(2-chloroethoxy)methane is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Bis(2-chloroethoxy)methane is a pharmaceutical intermediate identified by CAS number 111-91-1 and the molecular formula C5H10Cl2O2 and a molecular weight of 172.01 g/mol. Physically, the compound has a density of 1.2339 @ 20 °C/20 °C g/cm³, a solubility: ... Miscible with most organic solvents. Synonyms include BIS(2-CHLOROETHOXY)METHANE and Dichloroethylformal.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Bis(2-chloroethoxy)methane
Property Insights of Bis(2-chloroethoxy)methane
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bis(2-chloroethoxy)methane. With a topological polar surface area (TPSA) of 18.5 Ų, Bis(2-chloroethoxy)methane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bis(2-chloroethoxy)methane has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bis(2-chloroethoxy)methane?
The CAS number of Bis(2-chloroethoxy)methane is 111-91-1.
What is the molecular formula of Bis(2-chloroethoxy)methane?
The molecular formula of Bis(2-chloroethoxy)methane is C5H10Cl2O2.
What is the molecular weight of Bis(2-chloroethoxy)methane?
The molecular weight of Bis(2-chloroethoxy)methane is 172.00578 g/mol.
What are the applications of Bis(2-chloroethoxy)methane?
Bis(2-chloroethoxy)methane is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item...
Where can I buy Bis(2-chloroethoxy)methane?
You can request a quote for Bis(2-chloroethoxy)methane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bis(2-chloroethoxy)methane?
Yes, CoreyChem provides custom synthesis services for Bis(2-chloroethoxy)methane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.