Efonidipine Hydrochloride
TL;DR: Efonidipine Hydrochloride (CAS 111011-53-1) is a chemical compound with molecular formula C34H39ClN3O7P and molecular weight 667.22144 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate;hydrochloride
Also Known As: efonidipine hydrochloride, Efonidipine HCl, Efonidipine, Efonidipine (hydrochloride), NZ-105 hydrochloride
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C34H39ClN3O7P |
| Molecular Weight | 667.22144 g/mol |
| XLogP | 7.73 |
| Topological Polar Surface Area (TPSA) | 123.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 667.22144 Da |
| Heavy Atoms | 46 |
| Complexity | 1170.0 |
| SMILES | CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl |
| InChIKey | OXVTXPCIJDYQIS-UHFFFAOYSA-N |
Chemical Property Profile of Efonidipine Hydrochloride
Property Insights of Efonidipine Hydrochloride
The XLogP value of 7.73 indicates that Efonidipine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 123.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Efonidipine Hydrochloride. Following Lipinski's Rule of Five, Efonidipine Hydrochloride has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Efonidipine Hydrochloride?
The CAS number of Efonidipine Hydrochloride is 111011-53-1.
What is the molecular formula of Efonidipine Hydrochloride?
The molecular formula of Efonidipine Hydrochloride is C34H39ClN3O7P.
What is the molecular weight of Efonidipine Hydrochloride?
The molecular weight of Efonidipine Hydrochloride is 667.22144 g/mol.
Where can I buy Efonidipine Hydrochloride?
You can request a quote for Efonidipine Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Efonidipine Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Efonidipine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.