Pioglitazone
TL;DR: Pioglitazone (CAS 111025-46-8) is a chemical compound with molecular formula C19H20N2O3S and molecular weight 356.11948 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: Pioglitazone, Actos, Glustin, Zactos, Pioglitazona
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H20N2O3S |
| Molecular Weight | 356.11948 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 93.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 356.11948 Da |
| Heavy Atoms | 25 |
| Complexity | 466.0 |
| Melting Point | 193-194C |
| Solubility | Practically insoluble |
| SMILES | CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3 |
| InChIKey | HYAFETHFCAUJAY-UHFFFAOYSA-N |
Chemical Property Profile of Pioglitazone
Property Insights of Pioglitazone
The XLogP value of 3.8 indicates that Pioglitazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Pioglitazone. Following Lipinski's Rule of Five, Pioglitazone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Pioglitazone?
The CAS number of Pioglitazone is 111025-46-8.
What is the molecular formula of Pioglitazone?
The molecular formula of Pioglitazone is C19H20N2O3S.
What is the molecular weight of Pioglitazone?
The molecular weight of Pioglitazone is 356.11948 g/mol.
Where can I buy Pioglitazone?
You can request a quote for Pioglitazone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Pioglitazone?
Yes, CoreyChem provides custom synthesis services for Pioglitazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.