Ritolukast
TL;DR: Ritolukast (CAS 111974-60-8) is a chemical compound with molecular formula C17H13F3N2O3S and molecular weight 382.0599 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,1,1-trifluoro-N-[3-(quinolin-2-ylmethoxy)phenyl]methanesulfonamide
Also Known As: Ritolukastum, Ritolukast [USAN:INN], Ritolukastum [INN-Latin], RITOLUKAST [INN], Ritolukast (USAN/INN)
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H13F3N2O3S |
| Molecular Weight | 382.0599 g/mol |
| XLogP | 3.9 |
| Topological Polar Surface Area (TPSA) | 76.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 382.0599 Da |
| Heavy Atoms | 26 |
| Complexity | 565.0 |
| SMILES | C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=CC(=C3)NS(=O)(=O)C(F)(F)F |
| InChIKey | GOHUJGMYCZDYDF-UHFFFAOYSA-N |
Chemical Property Profile of Ritolukast
Property Insights of Ritolukast
The XLogP value of 3.9 indicates that Ritolukast is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Ritolukast. Following Lipinski's Rule of Five, Ritolukast has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Ritolukast?
The CAS number of Ritolukast is 111974-60-8.
What is the molecular formula of Ritolukast?
The molecular formula of Ritolukast is C17H13F3N2O3S.
What is the molecular weight of Ritolukast?
The molecular weight of Ritolukast is 382.0599 g/mol.
Where can I buy Ritolukast?
You can request a quote for Ritolukast directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Ritolukast?
Yes, CoreyChem provides custom synthesis services for Ritolukast and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.