4-Piperidin-1-yl-3-trifluoromethyl-phenylamine
TL;DR: 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine (CAS 112169-43-4) is a chemical compound with molecular formula C12H15F3N2 and molecular weight 244.11873 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-piperidin-1-yl-3-(trifluoromethyl)aniline
Also Known As: 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine, 4-(piperidin-1-yl)-3-(trifluoromethyl)aniline, 4-piperidin-1-yl-3-(trifluoromethyl)aniline, SP072, 8432AE
Technical Specifications
| Molecular Formula | C12H15F3N2 |
| Molecular Weight | 244.11873 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 29.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.11873 Da |
| Heavy Atoms | 17 |
| Complexity | 249.0 |
| SMILES | C1CCN(CC1)C2=C(C=C(C=C2)N)C(F)(F)F |
| InChIKey | RLYTXYOWWUWWND-UHFFFAOYSA-N |
Chemical Property Profile of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine
Property Insights of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine
The XLogP value of 3.1 indicates that 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.3 Ų, 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine?
The CAS number of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine is 112169-43-4.
What is the molecular formula of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine?
The molecular formula of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine is C12H15F3N2.
What is the molecular weight of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine?
The molecular weight of 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine is 244.11873 g/mol.
Where can I buy 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine?
You can request a quote for 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine?
Yes, CoreyChem provides custom synthesis services for 4-Piperidin-1-yl-3-trifluoromethyl-phenylamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.