Tetramethylpyrazine
TL;DR: Tetramethylpyrazine (CAS 1124-11-4) is a chemical compound with molecular formula C8H12N2 and molecular weight 136.10005 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,3,5,6-tetramethylpyrazine
Also Known As: 2,3,5,6-Tetramethylpyrazine, TETRAMETHYLPYRAZINE, Ligustrazine, Chuanxiongzine, Tetrapyrazine
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H12N2 |
| Molecular Weight | 136.10005 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 25.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 136.10005 Da |
| Heavy Atoms | 10 |
| Complexity | 87.0 |
| Purity | ≥98% |
| Melting Point | 86 °C |
| Boiling Point | 190.00 °C. @ 760.00 mm Hg |
| Solubility | slightly soluble in water; soluble in oils, propylene glycol, organic solvents |
| SMILES | CC1=C(N=C(C(=N1)C)C)C |
| InChIKey | FINHMKGKINIASC-UHFFFAOYSA-N |
Product Description
Applications: Tetramethylpyrazine is used in pharmaceutical synthesis routes and API production, as well as food, feed, and nutraceutical applications. It commonly serves as a versatile building block for organic synthesis. Typical specifications: commercial lots are supplied at ≥98%. CoreyChem supplies Tetramethylpyrazine (CAS 1124-11-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Tetramethylpyrazine is a pharmaceutical intermediate identified by CAS number 1124-11-4 and the molecular formula C8H12N2 and a molecular weight of 136.1 g/mol. Physically, the compound has a solubility: slightly soluble in water; soluble in oils, propylene glycol, organic solvents. It is also known as 2,3,5,6-Tetramethylpyrazine and TETRAMETHYLPYRAZINE.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H302, H315, H319, H335
Chemical Property Profile of Tetramethylpyrazine
Property Insights of Tetramethylpyrazine
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tetramethylpyrazine. With a topological polar surface area (TPSA) of 25.8 Ų, Tetramethylpyrazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tetramethylpyrazine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tetramethylpyrazine?
The CAS number of Tetramethylpyrazine is 1124-11-4.
What is the molecular formula of Tetramethylpyrazine?
The molecular formula of Tetramethylpyrazine is C8H12N2.
What is the molecular weight of Tetramethylpyrazine?
The molecular weight of Tetramethylpyrazine is 136.10005 g/mol.
What are the applications of Tetramethylpyrazine?
Tetramethylpyrazine is used in pharmaceutical synthesis routes and API production, as well as food, feed, and nutraceutical applications. It commonly serves as a versatile building block for organic synthesis. Typical specifications: commercial lots are supplied at ≥98%. CoreyChem supplies...
Where can I buy Tetramethylpyrazine?
You can request a quote for Tetramethylpyrazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tetramethylpyrazine?
Yes, CoreyChem provides custom synthesis services for Tetramethylpyrazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.