Imipramine Hydrochloride
TL;DR: Imipramine Hydrochloride (CAS 113-52-0) is a chemical compound with molecular formula C19H25ClN2 and molecular weight 316.17062 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride
Also Known As: Imipramine hydrochloride, Imipramine Hcl, Tofranil, Pryleugan, Chrytemin
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H25ClN2 |
| Molecular Weight | 316.17062 g/mol |
| XLogP | 4.3 |
| Topological Polar Surface Area (TPSA) | 6.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 316.17062 Da |
| Heavy Atoms | 22 |
| Complexity | 291.0 |
| Solubility | >47.5 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
| InChIKey | XZZXIYZZBJDEEP-UHFFFAOYSA-N |
Product Description
Applications: Imipramine Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Imipramine Hydrochloride (CAS 113-52-0) is a pharmaceutical intermediate with the molecular formula C19H25ClN2 and a molecular weight of 316.17 g/mol. Key physical properties include a solubility: >47.5 [ug/mL] (The mean of the results at pH 7.4). Synonyms include Imipramine hydrochloride and Imipramine Hcl.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Imipramine Hydrochloride
Property Insights of Imipramine Hydrochloride
The XLogP value of 4.3 indicates that Imipramine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Imipramine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Imipramine Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Imipramine Hydrochloride?
The CAS number of Imipramine Hydrochloride is 113-52-0.
What is the molecular formula of Imipramine Hydrochloride?
The molecular formula of Imipramine Hydrochloride is C19H25ClN2.
What is the molecular weight of Imipramine Hydrochloride?
The molecular weight of Imipramine Hydrochloride is 316.17062 g/mol.
What are the applications of Imipramine Hydrochloride?
Imipramine Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Imipramine Hydrochloride?
You can request a quote for Imipramine Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Imipramine Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Imipramine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.