Niguldipine
TL;DR: Niguldipine (CAS 113165-32-5) is a chemical compound with molecular formula C36H39N3O6 and molecular weight 609.2839 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: NIGULDIPINE, (S)-Niguldipine, Niguldipinum, Niguldipino, Niguldipine [INN]
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C36H39N3O6 |
| Molecular Weight | 609.2839 g/mol |
| XLogP | 6.8 |
| Topological Polar Surface Area (TPSA) | 114.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 11 |
| Exact Mass | 609.2839 Da |
| Heavy Atoms | 45 |
| Complexity | 1100.0 |
| SMILES | CC1=C([C@@H](C(=C(N1)C)C(=O)OCCCN2CCC(CC2)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC |
| InChIKey | SVJMLYUFVDMUHP-XIFFEERXSA-N |
Chemical Property Profile of Niguldipine
Property Insights of Niguldipine
The XLogP value of 6.8 indicates that Niguldipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Niguldipine. Following Lipinski's Rule of Five, Niguldipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Niguldipine?
The CAS number of Niguldipine is 113165-32-5.
What is the molecular formula of Niguldipine?
The molecular formula of Niguldipine is C36H39N3O6.
What is the molecular weight of Niguldipine?
The molecular weight of Niguldipine is 609.2839 g/mol.
Where can I buy Niguldipine?
You can request a quote for Niguldipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Niguldipine?
Yes, CoreyChem provides custom synthesis services for Niguldipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.