Bortezomib
TL;DR: Bortezomib (CAS 1133706-15-6) is a chemical compound with molecular formula C19H25BN4O4 and molecular weight 384.1969 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[3-methyl-1-[[3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
Also Known As: Bortezomib, (1S,2R)-Bortezomib, (1S,2S)-Bortezomib, Bortezomib Impurity Ps619, Bortezomib Impurity (R,S-Isomer)
Technical Specifications
| Molecular Formula | C19H25BN4O4 |
| Molecular Weight | 384.1969 g/mol |
| XLogP | 0.3606 |
| Topological Polar Surface Area (TPSA) | 124.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 384.1969 Da |
| Heavy Atoms | 28 |
| Complexity | 500.0 |
| SMILES | B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
| InChIKey | GXJABQQUPOEUTA-UHFFFAOYSA-N |
Chemical Property Profile of Bortezomib
Property Insights of Bortezomib
The XLogP value of 0.3606 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bortezomib. The TPSA of 124.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Bortezomib. Following Lipinski's Rule of Five, Bortezomib has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bortezomib?
The CAS number of Bortezomib is 1133706-15-6.
What is the molecular formula of Bortezomib?
The molecular formula of Bortezomib is C19H25BN4O4.
What is the molecular weight of Bortezomib?
The molecular weight of Bortezomib is 384.1969 g/mol.
Where can I buy Bortezomib?
You can request a quote for Bortezomib directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bortezomib?
Yes, CoreyChem provides custom synthesis services for Bortezomib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.