Baclofen
TL;DR: Baclofen (CAS 1134-47-0) is a chemical compound with molecular formula C10H12ClNO2 and molecular weight 213.05565 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-3-(4-chlorophenyl)butanoic acid
Also Known As: baclofen, Lioresal, Kemstro, Baclon, DL-Baclofen
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H12ClNO2 |
| Molecular Weight | 213.05565 g/mol |
| XLogP | -1.0 |
| Topological Polar Surface Area (TPSA) | 63.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 213.05565 Da |
| Heavy Atoms | 14 |
| Complexity | 191.0 |
| Melting Point | 372 to 376 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 64 °F (NTP, 1992) |
| SMILES | C1=CC(=CC=C1C(CC(=O)O)CN)Cl |
| InChIKey | KPYSYYIEGFHWSV-UHFFFAOYSA-N |
Chemical Property Profile of Baclofen
Property Insights of Baclofen
The XLogP value of -1.0 indicates that Baclofen is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 63.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Baclofen. Following Lipinski's Rule of Five, Baclofen has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Baclofen?
The CAS number of Baclofen is 1134-47-0.
What is the molecular formula of Baclofen?
The molecular formula of Baclofen is C10H12ClNO2.
What is the molecular weight of Baclofen?
The molecular weight of Baclofen is 213.05565 g/mol.
Where can I buy Baclofen?
You can request a quote for Baclofen directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Baclofen?
Yes, CoreyChem provides custom synthesis services for Baclofen and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.