Dotap
TL;DR: Dotap (CAS 113669-21-9) is a chemical compound with molecular formula C42H80NO4+ and molecular weight 662.60876 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl-trimethylazanium
Also Known As: DOTAP, Lipofectin, 1,2-Dotap, Dotap chloride, DOTMA
Technical Specifications
| Molecular Formula | C42H80NO4+ |
| Molecular Weight | 662.60876 g/mol |
| XLogP | 15.1 |
| Topological Polar Surface Area (TPSA) | 52.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 37 |
| Exact Mass | 662.60876 Da |
| Heavy Atoms | 47 |
| Complexity | 754.0 |
| SMILES | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC |
| InChIKey | KWVJHCQQUFDPLU-YEUCEMRASA-N |
Chemical Property Profile of Dotap
Property Insights of Dotap
The XLogP value of 15.1 indicates that Dotap is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.6 Ų, Dotap exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dotap has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Dotap?
The CAS number of Dotap is 113669-21-9.
What is the molecular formula of Dotap?
The molecular formula of Dotap is C42H80NO4+.
What is the molecular weight of Dotap?
The molecular weight of Dotap is 662.60876 g/mol.
Where can I buy Dotap?
You can request a quote for Dotap directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dotap?
Yes, CoreyChem provides custom synthesis services for Dotap and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.