(E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide
TL;DR: (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide (CAS 113874-05-8) is a chemical compound with molecular formula C12H11N3OS and molecular weight 245.06229 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[(E)-(5-methylthiophen-2-yl)methylideneamino]pyridine-3-carboxamide
Also Known As: (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide, N-[(E)-(5-methylthiophen-2-yl)methylideneamino]pyridine-3-carboxamide, Nicotinic acid [1-(5-methyl-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide
Technical Specifications
| Molecular Formula | C12H11N3OS |
| Molecular Weight | 245.06229 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 82.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 245.06229 Da |
| Heavy Atoms | 17 |
| Complexity | 295.0 |
| SMILES | CC1=CC=C(S1)/C=N/NC(=O)C2=CN=CC=C2 |
| InChIKey | LQRZUMOPGUMWIQ-RIYZIHGNSA-N |
Chemical Property Profile of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide
Property Insights of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide. The TPSA of 82.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide. Following Lipinski's Rule of Five, (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide?
The CAS number of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide is 113874-05-8.
What is the molecular formula of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide?
The molecular formula of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide is C12H11N3OS.
What is the molecular weight of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide?
The molecular weight of (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide is 245.06229 g/mol.
Where can I buy (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide?
You can request a quote for (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide?
Yes, CoreyChem provides custom synthesis services for (E)-N'-((5-methylthiophen-2-yl)methylene)nicotinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.