(E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide
TL;DR: (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide (CAS 1164461-27-1) is a chemical compound with molecular formula C23H17ClN4OS and molecular weight 432.08115 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E)-N-[5-[(3-chlorophenyl)methyl]-1,3-thiazol-2-yl]-2-cyano-3-(1-methylindol-3-yl)prop-2-enamide
Also Known As: (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide, (E)-N-[5-(3-Chloro-benzyl)-thiazol-2-yl]-2-cyano-3-(1-methyl-1H-indol-3-yl)-acrylamide, (2E)-N-[5-(3-chlorobenzyl)-1,3-thiazol-2-yl]-2-cyano-3-(1-methyl-1H-indol-3-yl)prop-2-enamide, (2E)-N-{5-[(3-chlorophenyl)methyl](1,3-thiazol-2-yl)}-2-cyano-3-(1-methylindol -3-yl)prop-2-enamide, (E)-N-[5-[(3-chlorophenyl)methyl]-1,3-thiazol-2-yl]-2-cyano-3-(1-methylindol-3-yl)prop-2-enamide
Technical Specifications
| Molecular Formula | C23H17ClN4OS |
| Molecular Weight | 432.08115 g/mol |
| XLogP | 5.7 |
| Topological Polar Surface Area (TPSA) | 99.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 432.08115 Da |
| Heavy Atoms | 30 |
| Complexity | 707.0 |
| SMILES | CN1C=C(C2=CC=CC=C21)/C=C(\C#N)/C(=O)NC3=NC=C(S3)CC4=CC(=CC=C4)Cl |
| InChIKey | AHNAJLLEGVPEGG-LFIBNONCSA-N |
Chemical Property Profile of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide
Property Insights of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide
The XLogP value of 5.7 indicates that (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide. Following Lipinski's Rule of Five, (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide?
The CAS number of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide is 1164461-27-1.
What is the molecular formula of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide?
The molecular formula of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide is C23H17ClN4OS.
What is the molecular weight of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide?
The molecular weight of (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide is 432.08115 g/mol.
Where can I buy (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide?
You can request a quote for (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide?
Yes, CoreyChem provides custom synthesis services for (E)-N-(5-(3-chlorobenzyl)thiazol-2-yl)-2-cyano-3-(1-methyl-1H-indol-3-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.